A GENERAL THEORY OF GLACIER SURGES

A general theory of glacier surges

We present the first general theory of glacier surging that includes both temperate and polythermal glacier surges, based on coupled mass and enthalpy budgets.Enthalpy (in the form of thermal energy and water) is gained at the glacier bed from geothermal heating plus frictional heating (expenditure of potential energy) as a consequence of ice flow.

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Investigation of a Multi-Strategy Ensemble Social Group Optimization Algorithm for the Optimization of Energy Management in Electric Vehicles

A multi-strategy ensemble social group optimization algorithm (ME-SGO) to improve the exploration for complex and composite landscapes through distance-based strategy adaption and success-based parameter adaption while incorporating linear population reduction is proposed.The proposed method is designed to achieve a better balance between explorati

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Folic acid restricts SARS-CoV-2 invasion by methylating ACE2

The current COVID-19 pandemic is motivating us to elucidate the Graters molecular mechanism of SARS-CoV-2 invasion and find methods for decreasing its transmissibility.We found that SARS-CoV-2 could increase the protein level of ACE2 in mice.Folic acid and 5-10-methylenetetrahydrofolate reductase (MTHFR) could promote the methylation of the ACE2 pr

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MICROVASCULAR CHANGES AND DIABETIC RETINOPATHY AND NEPHROPATHY PROGRESSION IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS

Background: We established that the age at inception of T1DM significantly impacts the long-term risk of developing proliferative retinopathy in affected children and adolescents.Patients with T1DM, diagnosed before the age of 15 are at a significantly higher risk than children diagnosed at age 15 and older.For instance, several studies show change

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